Fig. 1 | Scientific Reports

Fig. 1

From: Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate

Fig. 1

Characterization of P. aeruginosa U804 (a) Circular genome map of U804 including the 163 longest contigs. From outer to inner rings: the contigs, CDS on the forward strand, CDS on the reverse strand, RNA genes, CDS with homology to known antimicrobial resistance genes, CDS with homology to known virulence factors, GC content and GC skew. The colors of the CDS on the forward and reverse strand indicate the subsystem that these genes belong to (b) Subsystem distribution of genes within the U804 genome (c) ProgressiveMauve alignment of U804 scaffolds to laboratory reference strain PAO1 highlights a non-homology block spanning 2.09 Mb to 2.42 Mb in PAO1, approximately 334 Kb in length. The missing region includes hmgA and galU which, when absent, result in pyomelanin production and phage resistance (d) Effect of Tyrosine and (e) Ascorbic acid on pyomelanin production by P. aeruginosa U804. Data are shown as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 compared with untreated by determining One-way ANOVA.

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