Fig. 1
From: Generation and propagation of high fecundity gene edited fine wool sheep by CRISPR/Cas9
Schematic diagram of precise editing BMPRIB by CRISPR/Cas9 -mediated HDR. SgRNA-targeting sequence is onlined and the PAM sequence is indicated in green. Exon 8 is indicated by closed box. The red nucleotide ‘A’ and ‘G’ are the target site of the intended mutation (c.746 A > G; p.Q249R). The amino acids are indicated by capital letters, with the amino acid variation indicated by the blue frame. ssODN, single-stranded oligo deoxynucleotide.
