Fig. 2
From: NLRP3 overexpression exacerbated synovium tissue degeneration in juvenile collagen-induced arthritis
NRLP3 overexpression exacerbates the severity of the general and behavior condition of CIA rats. The rats were divided randomly into six groups: (sham group, CIA group, NC-KD group, KD-NLRP3 group, OE-NC group, and OE-NLRP3 group, with 8 rats in each group). (a) arthritis score; (b) body weight; (c) hind paw thickness; (d) mechanical pain assessment; (e) thermal pain assessment. Values are expressed as means ± SD, ns: non-significant, *P < 0.05, **P < 0.01, ***P < 0.001 versus the CIA group.
