Fig. 3
From: NLRP3 overexpression exacerbated synovium tissue degeneration in juvenile collagen-induced arthritis
NLRP3 overexpression promoted CIA-induced synovial inflammation. The rats were divided randomly into six groups: (sham group, CIA group, NC-KD group, KD-NLRP3 group, OE-NC group, and OE-NLRP3 group, with 8 rats in each group). (A), Safranin-O and H&E staining of the knee joint and OARSI score (scale bar = 500 μm).; (B) H&E staining of the synovium of the knee joint and histological score (scale bar = 100 μm). Data are presented as the mean ± SD.*, P < 0.05; **, P < 0.01. ns: not significant.
