Fig. 2 | Scientific Reports

Fig. 2

From: Application of drug-induced growth rate inhibition and intracellular drug exposures for comprehensive evaluation of cellular drug sensitivity

Fig. 2

Total and unbound cell associated drug concentrations for auristatins: Mean total cell associated drug concentrations (Eq. 1) versus time profiles for cells treated at respective media GR50 drug concentrations (A). Data presents mean ± sd from n = 3 biological replicates in one experiment. A tabulation of cellular partition coefficient (Kp (total) and Kpuu (unbound)), and intracellular total and unbound GR50 drug concentrations (Eqs. 2–5) for each auristatin in the different cell lines/type.

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