Table 1 Cardiovascular magnetic resonance imaging baseline.
Variable | NCD baseline | HFpEF baseline | HFpEF IASD | NCD vs. HFpEF | NCD vs. IASD | HFpEF vs. IASD |
|---|---|---|---|---|---|---|
Laboratory testing | ||||||
NTproBNP | 55 (37, 111) | 209 (80, 320) | 230 (141, 998) | 0.004 | 0.002 | 0.368 |
Echocardiography | ||||||
E/e’ | 9.6 (8.6, 12.0) | 11.5 (10.3, 13.5) | 12.8 (9.1, 12.9) | 0.063 | 0.263 | 0.958 |
TAPSE | 21.8 (19.1, 26.4) | 23.6 (21.0, 28.8) | 25.6 (23.1, 28.5) | 0.447 | 0.145 | 0.562 |
Right heart catheterisation | ||||||
Pulmonary vascular resistance | 1.48 | 1.71 | 1.05 | 0.218 | 0.263 | 0.007 |
Left ventricle | ||||||
LV Mass | 55.3 (48.1, 72.2) | 52.2 (47.9, 62.1) | 60.0 (47.0, 67.5) | 0.631 | 0.958 | 0.562 |
LV EDV | 65.9 (54.9, 80.3) | 65.3 (60.7, 75.7) | 59.0 (51.6, 74.4) | 0.853 | 0.562 | 0.263 |
LV ESV | 19.6 (13.0, 23.3) | 16.7 (14.3, 24.5) | 17.1 (14.7, 26.4) | 0.971 | 0.875 | 0.875 |
LV SV | 45.1 (40.0, 59.2) | 49.3 (44.3, 55.1) | 44.6 (33.0, 51.0) | 0.579 | 0.492 | 0.220 |
LV EF | 73.4 (63.9, 77.2) | 75.8 (66.5, 77.2) | 71.6 (58.4, 75.8) | 0.579 | 0.562 | 0.220 |
FT LV GLS | −26.6 (−23.4, −29.2) | −27.2 (−21.2, −30.4) | −23.4 (−20.8, −26.8) | 0.912 | 0.220 | 0.313 |
FT LV GCS | −37.2 (−40.0, −34.1) | −37.4 (−32.2, −41.2) | −40.8 (−28.4, −43.5) | 0.796 | 0.635 | 0.713 |
LV LAS rest | 13.7 (13.1, 15.4) | 13.8 (11.5, 15.5) | 12.3 (7.5, 13.9) | 1.000 | 0.093 | 0.181 |
LV LAS stress | 17.8 (13.9, 20.7) | 15.6 (12.9, 17.5) | 13.6 (11.6, 17.0) | 0.353 | 0.147 | 0.368 |
Septal Native T1 | 1314 (1288, 1335) | 1302 (1264, 1334) | 1344 (1289, 1395) | 0.696 | 0.414 | 0.181 |
Septal ECV | 24.9 (21.8, 26.9) | 25.6 (24.4, 29.2) | 25.0 (24.9, 27.0) | 0.156 | 0.456 | 0.492 |
Left atrium | ||||||
FT LA Es | 27.1 (20.7, 29.6) | 22.8 (13.9, 24.6) | 20.7 (14.4, 24.5) | 0.075 | 0.073 | 0.875 |
FT LA Ee | 12.2 (6.5, 17.2) | 11.0 (6.5, 13.5) | 8.5 (7.9, 12.7) | 0.353 | 0.713 | 0.792 |
FT LA Ea | 12.7 (11.2, 16.8) | 10.5 (6.2, 13.5) | 10.0 (6.2, 13.7) | 0.105 | 0.118 | 1.000 |
LA LAS rest | 21.0 (19.4, 23.3) | 12.8 (8.5, 20.9) | 12.1 (8.2, 16.4) | 0.052 | < 0.001 | 0.713 |
LA LAS stress | 20.5 (15.7, 28.9) | 18.3 (13.2, 20.5) | 13.0 (8.9, 18.5) | 0.247 | 0.073 | 0.263 |
Right ventricle | ||||||
RV EDV | 64.6 (48.4, 76.6) | 65.0 (58.1, 71.7) | 65.1 (51.3, 81.4) | 0.739 | 0.875 | 1.000 |
RV ESV | 22.4 (16.1, 28.7) | 20.0 (16.4, 23.0) | 23.2 (16.9, 29.2) | 0.529 | 0.792 | 0.562 |
RV SV | 42.5 (34.8, 48.8) | 45.6 (38.7, 51.3) | 44.1 (28.9, 55.8) | 0.393 | 1.000 | 0.792 |
RV EF | 65.3 (60.7, 70.9) | 69.5 (63.7, 74.9) | 64.8 (60.2, 68.9) | 0.218 | 0.875 | 0.263 |
RV LAS rest | 18.3 (16.8, 22.2) | 26.3 (20.9, 30.3) | 18.0 (16.8, 20.9) | 0.015 | 0.713 | 0.011 |
RV LAS stress | 18.9 (15.1, 23.3) | 24.2 (21.2, 27.3) | 21.6 (19.2, 27.0) | 0.052 | 0.263 | 0.428 |
