Table 1 Clinical data of the 8 patients.
From: Longitudinal MRI evaluation of the efficacy of non-enhanced lung cancer brain metastases
Case | Gender | Age | Site of lung cancer | Site of BM | Number of BM | Annotation | Size of BM | Stage of lung cancer | Enhancement type | Treatment | Efficacy evaluation |
|---|---|---|---|---|---|---|---|---|---|---|---|
P1 | Female | 57 | Inferior lobe of left lung | Left frontal lobe | 1 | — | 0.6 × 0.6 cm | T1N2M1 IV | Mild enhanced → enhanced | Chemotherapy + targeted therapy + immunotherapy + radiotherapy | PR |
P2 | Male | 69 | Inferior lobe of left lung | Left cerebellum | 1 | — | 0.5 × 0.6 cm | T4N3M1 IV | Non-enhanced | Chemotherapy + targeted therapy + radiotherapy | PD |
P3 | Female | 59 | Middle lobe of right lung | Right parietal lobe | 1 | — | 0.8 × 0.9 cm | T2N0M1 IV | Non-enhanced | Chemotherapy + radiotherapy + immunotherapy | PD |
P4 | Male | 47 | Superior lobe of left lung | Right parietal lobe | 1 | — | 1.6 × 1.7 cm | T1N2M1 | Non-enhanced | Chemotherapy + + radiotherapy + targeted therapy | PD |
P5 | Male | 73 | Superior lobe of right lung | Left frontal lobe | 1 | Foci 1 | 2.2 × 2.8 cm | T2N0M1 IV | Obvious enhanced | Chemotherapy + targeted therapy + radiotherapy | PR |
Left parietal lobe | 1 | Foci 2 | 0.6 × 0.9 cm | Non-enhanced | PD | ||||||
P6 | Female | 54 | Inferior lobe of left lung | Left frontal lobe | 1 | Foci 1 | 1.7 × 2.1 cm | T4N0M1 IV | Obvious enhanced | Chemotherapy + targeted therapy + radiotherapy | PR |
Left thalamus | 1 | Foci 2 | 3.2 × 3.6 cm | Obvious enhanced→Non-enhanced | SD | ||||||
P7 | Male | 33 | Inferior lobe of right lung | Left temporal lobe | 1 | Foci 1 | 1.0 × 1.3 cm | T1N3M1 IV | Enhanced | Chemotherapy + immunotherapy + targeted therapy + radiotherapy | CR |
Brainstem | 1 | Foci 2 | 0.6 × 0.7 cm | Non-enhanced | CR | ||||||
P8 | Male | 71 | Inferior lobe of left lung | Left temporal lobe | 4 | Foci 1 | 1.6 × 1.8 cm | T1bN2M1 IV | Enhanced | Chemotherapy + immunotherapy + targeted therapy + radiotherapy | CR |
Right temporal lobe | 1 | Foci 2 | 1.7 × 1.7 cm | Non-enhanced | PR |