Table 1 Baseline characteristics of study patients.

From: Efficacy of continuous venovenous hemodiafiltration in patients with metformin associated lactic acidosis and acute kidney injury

Patients

27

Female

20

 

Mean (range)

Age (years)

69.2 (44–86)

Weight (kg)

72.3 (50–100)

Female

Male

72.7 (50–100)

71.3 (60–90)

Glasgow coma scale

13.7 (5–15)

Metformin daily dose (mg)

2330.4 (1000–3000)

Comorbidities

• Hypertension: 19

• Obesity: 12

• COPD: 3

• PAD: 2

• Cancer history: 3

• CAD: 3

• Stroke 1

• Hydrocephalus: 1

Causes for dehydration

• 22/27 Gastroenteric

(vomit and/or diarrhea)

• 10/27 Fever

• 2/27 Reduced water intake

Drugs

• 8/27 ACEIs

• 6/27 ARBs

• 2/27 NSAID

Blood pressure* (mmHg)

Systolic BP (SBP): 109 ± 35.5

Diastolic BP (DBP): 58.6 ± 16.95

Mean BP**: 75.4 ± 23.1

Catecholamines

One

Two

Total

6/27

2/27

8/27

CKD

1/27 (stage III-B)

  1. COPD: Chronic obstructive pulmonary disease, PAD: Peripheral artery disease, CAD: coronary artery disease, ACEIs: Angiotensin-Converting Enzyme Inhibitors, ARBs: Angiotensin receptor blockers, NSAID: Non-steroidal anti-inflammatory drugs
  2. *Mean and standard deviation
  3. **Mean blood pressure calculated with the formula: DBP + (SBP-DBP)/3