Table 4 CVVHDF anticoagulation.

From: Efficacy of continuous venovenous hemodiafiltration in patients with metformin associated lactic acidosis and acute kidney injury

CVVHDF anticoagulation

 

Heparin (n. pts)

RCA (n. pts)

 

20

13*

Anticoagulation

Mean dose (U/kg/h)

Mean iCa-s (mmol/l)

 

4.4 (2.7–20)

1.1 (0.93–1.23)

 

Mean ACT value (sec)

Mean tCa/iCa ratio

 

165.9 (144–200)

2.1 (1.78–2.74)

Mean treatment time (h)

50.5 (24–120)

68.3 (24–144)

Downtime (min)

23.3 (0-120)

8.1 (0–90)

  1. (CVVHDF: continuous venovenous hemodiafiltration, RCA: regional citrate anticoagulation, ACT: activated clotting time, tCa: total plasma calcium, iCa: ionized calcium)
  2. *6 patients were shifted from heparin to RCA; for these patients treatment time was evaluated separately.
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