Table 1 Kinetics of Hemagglutination inhibition (HI) antibody response in cattle vaccinated with different doses of inactivated H5 avian influenza vaccine.

From: Evaluation of humoral immune response and milk antibody transfer in calves and lactating cows vaccinated with inactivated H5 avian influenza vaccine

Weeks post-vaccination

Mean HI Antibody titer (log2)

Group (1)

4 × (2 ml)

Group (2)

6 × (3 ml)

Group (3)

8 × (4 ml)

Group (4)

12 × (6 ml)

Group (6)

Non vaccinated

1st

*4

5

5

6

0

2nd

6

7

8

9

0

3rd

6

7

8

8

0

4th

6

8

9

9

0

5th

6

8

9

9

0

6th

6

8

9

9

0

**p-value

0.0018

***χ2

15

  1. *A minimum HI titer of ≥ 5 log2 is considered the serological potency standard for protecting birds against mortality, while HI titers ≥ 7 log2 can prevent virus shedding from the oropharynx in vaccinated birds.
  2. **p-value Ë‚ 0.05 is significant.
  3. ***The Friedman test statistic (chi-square value) denoted as χ2.
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