Table 1 Baseline characteristics of AIS patients on all cohorts.

From: Noninvasive imaging biomarker reveals invisible microscopic variation in acute ischaemic stroke (≤ 24 h): a multicentre retrospective study

Characteristic

Training and internal validation set

Cohort 6

Cohort 7

Cohort 8

No. of patients

592

204

53

273

Gender

    

Female

195 (32.9)

64 (31.4)

13 (24.5)

90 (33.0)

Male

397 (67.1)

140 (68.6)

40 (75.5)

183 (67.0)

Age*

63 (26–96)

64.5 (21–95)

65 (40–84)

68 (26–95)

< 40y

11 (1.9)

8 (3.9)

0 (0.0)

4 (1.5)

40-49y

68 (11.5)

10 (4.9)

1 (1.9)

22 (8.1)

50-59y

157 (26.5)

53 (26.0)

18 (34.0)

44 (16.1)

60-69y

187 (31.6)

66 (32.4)

14 (26.4)

83 (30.4)

≥ 70y

169 (28.5)

67 (32.8)

20 (37.7)

120 (43.9)

Systolic blood pressure

    

≥ 140mmHg

411 (69.4)

166 (81.4)

36 (67.9)

188 (68.9)

< 140mmHg

181 (30.6)

38 (18.6)

17 (32.1)

85 (31.1)

Diastolic blood pressure

    

≥ 90mmHg

208 (35.1)

57 (27.9)

24 (45.3)

90 (33.0)

< 90mmHg

384 (64.9)

147 (72.1)

29 (54.7)

183 (67.0)

History

    

Hypertension

391 (66.0)

137 (67.2)

40 (75.5)

198 (72.5)

Dyslipidaemia

155 (26.2)

74 (36.3)

19 (35.8)

51 (18.7)

Diabetes

187 (31.6)

67 (32.8)

16 (30.2)

109 (39.9)

Coronary artery disease

160 (27.0)

44 (21.6)

5 (9.4)

27 (9.9)

Smoking

247 (41.7)

94 (46.1)

32 (60.4)

89 (32.6)

Drinking

227 (38.3)

96 (47.1)

26 (49.1)

93 (34.1)

From onset to MRI scan

    

≤ 48 h

318 (53.7)

128 (62.7)

24 (45.3)

69 (25.3)

> 48 h

274 (46.3)

76 (37.3)

29 (54.7)

204 (74.7)

The interval from CT to MRI scan / h (median, IQR)

29.3 (14.9, 61.6)

22.5 (11.4, 46.5)

21.7 (11, 33.6)

20.4 (10.7, 28.5)

  1. AIS, Acute ischemic stroke;.
  2. Note. Unless otherwise specified, data in parentheses are percentages.
  3. *Numbers in parentheses are the range.