Table 2 Relative contribution of interfacial tension reduction (\(\Delta \gamma _{cc}\)) and cortical tension increase (\(\Delta \gamma _{cm}\)) to tension polarization factor, \(\mathcal {P}\), under various pharmacological treatments. \(\left\langle \cdot \right\rangle\) denotes group average.
From: N-Cadherin based adhesion and Rac1 activity regulate tension polarization in the actin cortex
Parameter | Control | 50 µM | 15 nM | 30 nM | 45 nM |
|---|---|---|---|---|---|
LAN-High | Blebbistatin | NSC | NSC | NSC | |
\(\left\langle \Delta \gamma _{cm}\right\rangle /\left\langle \gamma _{0}\right\rangle\) | 0.32 | 0 | 0.26 | 0.18 | 0.16 |
\(\left\langle \Delta \gamma _{cc}\right\rangle /\left\langle \gamma _{0}\right\rangle\) | 0.27 | 0.23 | 0.20 | 0.17 | 0.20 |
\(\left\langle \mathcal {P}\right\rangle\) | 0.59 | 0.23 | 0.46 | 0.35 | 0.36 |
Cortical tension | 54% | 0% | 57% | 50% | 44% |
increase contribution | |||||
Interfacial tension | 46% | 100% | 43% | 50% | 56% |
reduction contribution |
