Fig. 2 | Scientific Reports

Fig. 2

From: Histone demethylase inhibitor KDM5-C70 regulates metabolomic and lipidomic programming during an astrocyte differentiation of rat neural stem cell

Fig. 2

Determination of KDM5-C70 treatment-related metabolites and enriched metabolic networks of endogenous metabolites. (A) OPLS-DA score plot indicating the clustering of the control and KDM5-C70 groups. (B) Metabolites with VIP scores > 1.0. (C) Volcano plot of all identified metabolites. (D) Metabolic network constituted with KDM5-C70 associated metabolic pathways. Metabolites with a VIP score greater than 1.0 are highlighted with a red border. In the bar graph, the control group is represented in blue, whereas the KDM5-C70 group is represented in red. Biomarkers are emphasized with a yellow background.

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