Fig. 5 | Scientific Reports

Fig. 5

From: Histone demethylase inhibitor KDM5-C70 regulates metabolomic and lipidomic programming during an astrocyte differentiation of rat neural stem cell

Fig. 5

mRNA expression levels of genes involved in PE biosynthesis. (A) PE biosynthesis metabolism and its associated regulators. (B–G) Etnk1, Etnk2, Pcyt2, Selenoi, Pisd, and Plaat3 mRNA expression levels were determined using real-time RT-PCR. Total RNA was extracted from NSCs treated with 0.1% DMSO or 25 µM KDM5-C70 in the absence of EGF and FGF2 for 3 days. Gapdh was used as an internal control. Data are presented as the mean ± SEM (n = 3). * p < 0.05, ** p < 0.01 (Student’s t-test).

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