Fig. 7

ROC Curve of the Hub with multiple curves with AUC values labeled as 0.501 (cyan curve), 0.516 (orange curve), and 0.339 (purple curve). The cyan and orange curves show weak predictive power, while the purple curve has the lowest AUC (0.339). The purple curve indicates poor performance, worse than random guessing.Models with lower AUC values are less reliable for biomarker identification and indicates weaker models overall, with no curve achieving strong predictive performance.