Table 3 The bioavailability score and pharmacokinetics of derivatives calculated with the SWISS ADME database.
Ligand | GI abs | Bioavailability score | BBB | P-gp substrate | CYP1A2 | CYP2C19 | CYP2C9 | CYP2D6 | CYP3A4 |
|---|---|---|---|---|---|---|---|---|---|
I-1 | Low | 0.55 | No | No | No | Yes | Yes | No | Yes |
Acarbose | Low | 0.17 | No | Yes | No | No | No | No | No |
