Table 5 Effect of compound I-1 on body weight and insulin level. Values are presented as Mean ± SEM (no. Of animals, n = 6) and were significantly different at ### p < 0.001 in comparison to normal control group, while *** p < 0.001, **p < 0.01, ns = p > 0.05 when compared with diabetic control group.

Control

193.23 ± 1.24

196.35 ± 1.45

189.35 ± 1.56

0.73 ± 0.12

0.79 ± 0.87

Diabetic

188.86 ± 2.12^ns

178.80 ± 1.63^###

148.65 ± 2.54^###

0.84 ± 0.26^ns

0.55 ± 0.13^ns

Acarbose

179.98 ± 1.67^ns

162.74 ± 2.24^**

178.90 ± 4.24^***

0.82 ± 0.54^ns

0.80 ± 0.18^ns

I-1 (10 Mg)

191.23 ± 1.50^ns

156.28 ± 3.50^***

182.43 ± 4.70^***

0.80 ± 0.28^ns

0.67 ± 0.25^ns

I-1 (20 Mg)

200.23 ± 1.76^ns

147.34 ± 1.50^ns

188.38 ± 5.67^***

0.76 ± 0.48^ns

0.75 ± 0.18^ns

I-1 (30 Mg)

204.66 ± 3.60^***

171.60 ± 1.90^ns

198.19 ± 4.66^***

0.73 ± 0.38^ns

0.70 ± 0.12^ns