Table 3 Local histopathological examination.

From: Biodegradability and biocompatibility test of Magnesium Carbonate apatite composite implants fabricated by extrusion technique on Sprague Dawley Rats

Parameters

None or minimal; n(%)

Mild; n(%)

Moderate; n(%)

Severe; n(%)

Very severe; n(%)

P value

Inflammatory cell infiltration

      

Titanium

1 (16.7)

3 (50.0)

1 (16.7)

0 (0)

1 (16.7)

0.715

Mg0CA

0 (0)

2 (33.3)

1 (16.7)

1 (16.7)

2 (33.3)

 

Mg5CA

1 (16.7)

2 (33.3)

0 (0)

0 (0)

3(50.0)

 

Mg10CA

0 (0)

2 (33.3)

1 (16.7)

2 (33.3)

1 (16.7)

 

Mg15CA

0 (0)

3(50.0)

2 (33.3)

0 (0)

1 (16.7)

 

Soft tissue scoring

      

Titanium

1 (16.7)

3 (50.0)

1 (16.7)

0 (0)

1 (16.7)

0.373

Mg0CA

0 (0)

0 (0)

3 (50.0)

2 (33.3)

1 (16.7)

 

Mg5CA

0 (0)

3 (50.0)

0 (0)

0 (0)

3 (50.0)

 

Mg10CA

0 (0)

2 (33.3)

1 (16.7)

2 (33.3)

1 (16.7)

 

Mg15CA

0 (0)

1 (16.7

5 (83.3)

0 (0)

0 (0)

 

Neovascularization

      

Titanium

1 (16.7)

3 (50.0)

1 (16.7)

0 (0)

1 (16.7)

0.505

Mg0CA

0 (0)

1 (16.7)

3 (50.0)

1 (16.7)

1 (16.7)

 

Mg5CA

0 (0)

3 (50.0)

0 (0)

0 (0)

3 (50.0)

 

Mg10CA

0 (0)

2 (33.3)

1 (16.7)

2 (33.3)

1 (16.7)

 

Mg15CA

0 (0)

3 (50.0

2 (33.3)

0 (0)

1 (16.7)

 

Local osteoclast count

      

Titanium

5 (83.3)

1 (16.7)

0 (0)

0 (0)

0 (0)

0.220

Mg0CA

2 (33.3)

2 (33.3)

1 (16.7)

1 (16.7)

0 (0)

 

Mg5CA

0 (0)

3 (50.0)

1 (16.7)

2 (33.3)

0 (0)

 

Mg10CA

3 (50.0)

1 (16.7)

1 (16.7)

1 (16.7)

0 (0)

 

Mg15CA

5 (83.3)

0 (0)

0 (0)

0 (0)

0 (0)

 

Osteoblast activity

      

Titanium

1 (16.7)

3 (50.0)

1 (16.7)

1 (16.7)

0 (0)

0.468

Mg0CA

0 (0)

2 (33.3)

2 (33.3)

2 (33.3)

0 (0)

 

Mg5CA

0 (0)

2 (33.3)

1 (16.7)

1 (16.7)

2 (33.3)

 

Mg10CA

0 (0)

2 (33.3)

2 (33.3)

1 (16.7)

1 (16.7)

 

Mg15CA

0 (0)

3 (50.0)

2 (33.3)

1 (16.7)

0 (0)