Table 1 A list of reported possible biomarkers of TB identified from human breath and mycobacterium culture across different studies.
From: New volatile organic compounds from the exhaled breath of active tuberculosis patients
Sample type | Compounds | Analysis Technique | Ref |
|---|---|---|---|
Breath | Naphthalene 2,3,6-trimethyl-, Heptane 4-ethyl-2,2,6,6-tetramethyl-, Indane, 2,2,3-trimethylhexane, 1-Hexene-6-phenyl-4-(1-phenylethoxy)-, Butyl acetate, 1,2,3-trimethylbenzene, 2,2,4,6,6-pentamethylheptane, 4-(2-methylbutan-2-yl) phenol, Ethyl butyrate, 4-methyl-1-decene | GC + GC-TOFMS | |
Breath | Decane, 4-methyloctane | GC + GC-TOFMS | |
Breath | 1,4-Dichlorobenzene, Trans-1,3-Dimethylcyclohexane, 1,4-Dimethylcyclohexane, 1-Octanol 2-butyl, 1-Methylnaphthalene, Camphene, 4-Methyldecane, 3-Ethyl-2-methylheptane, 2,6-Dimethyloctane, 1,2,3,4-Tetramethylbenzene,Bicyclo 3.1.1 hept-2-ene, 3,6,6-trimethyl-, trans-1-Ethyl-4-Methlcylohexane. | ATD-GC-MS, | |
Breath | Oxetane 3-(1-methylethyl)-, 4-Methyldodecane, Hexylcyclohexane, Bis-(3,5,5-trimethylhexyl) phthalate, 1,3,5-trimethylbenzene, 3,7-Dimethyldecane, Tridecane, 4,6,8-Trimethyl-1-nonene, 5-Ethyl-2-methylheptane, 4-Methyl-1-hexene | ATD-GC-MS | |
Culture | 1-Methylnaphthalene, 3-heptanone, 2,2,4,6,6-Pentamethylheptane, Benzene 1-methyl-4-(1-methylethyl)-, 1,4-Dimethylcyclohexane, 3,5-dimethylamphetamine, Methylcyclododecane, 3-Methylbutanal, 2-hexene, Trans-anti-1-methyldecahydronaphthalene | ATP-GC-MS | |
Culture | Hexadecanoic acid, Decane, Dodecane, Tridecane, 2-Methyltridecane, tridecanol, Octadecanoic acid, Isotridecanol, Eicosonoic acid, Nonadecanoic acid | GC + GC-TOFMS | |
Culture | Cyclohexanone 2-(dimethylamino)-, 2-propanamine, isobutyronitrile, ethane, isocyanato-, dodecane, cyclohexanone, 3-pentene-2-one, Methanethioanide N N-dimethyl-, Ethanamine N-methyl | GC-TOF-MS | |
Culture | 4-ethyl-2,2,6,6-tetramethlheptane, 2-ethylhexyl isobutyl sulfite, 3-hydroxy-3-methylbutanoic acid, 2-Pinene, Azulene, Heptanal, 1-propynylbenzene, 2,3,6-trimethylheptane, 1,2-xylene, 4-ethyl decane, 2,5-dimethyldecane, 1-nitroadamantane, 2,6-dimethylheptadecane, beta-phellandrene, 4-tert-Amyl phenol | GC + GC-TOFMS |
