Fig. 1

Differential expression of F2RL1 in CCa. (A)The expression of F2RL1 in pan-cancer from TCGA + GTEx database.(B)F2RL1 mRNA expression shows a marked increase in CCa tissues compared to normal tissues.(C) Validation of F2RL1 differential expression in the GES63678 dataset.(D) F2RL1 has differentially expressed between squamous and adenocarcinomas in CCa.(E–G) The expression of F2RL1 in different pathological stages.(H-J)Immunohistochemical staining of the F2RL1 protein in CCa tissue sections. (H) normal tissue, (I) squamous carcinoma, and (J) adenocarcinoma. * p < 0.05, ** p < 0.01, *** p < 0.001.