Fig. 4 | Scientific Reports

Fig. 4

From: Flavonolignans silybin, silychristin and 2,3-dehydrosilybin showed differential cytoprotective, antioxidant and anti-apoptotic effects on splenocytes from Balb/c mice

Fig. 4

Extracellular nitric oxide (NO) production by untreated control splenocytes (Ctrl) and cells treated with 5 or 50 μmol/ml of silybin (SB), silychristin (SCH), and 2,3-dehydrosilybin (DHSB) (a), after 24 h incubation alone or in combination with AAPH (b). Data are expressed in μM of NO produced by 1 × 106 cells/ml and represent means ± SD (n = 6). Significantly different values between groups indicated by lines are marked as: *p < 0.05, **p < 0.01, ***p < 0.001, ns—not significant.

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