Table 3 Evaluation of HLA Haplotyping Bioinformatics Module.

From: Exome sequencing shows same pattern of clonal tumor mutational burden, intratumor heterogenicity and clonal neoantigen between autologous tumor and Vigil product

Locus

Gradalis vs. Abi-Rached

Gradalis vs. Abi-Rached %

Additional Matches to Thuesen

% Match to Abi-Rached or Thuesen

Remaining non-matching haplotype calls

Thuesen % Correct (820 samples—adjusted

HLA-A

88

88.9%

8

97.0%

3

92.80%

HLA-B

92

92.9%

6

99.0%

1

97.80%

HLA-C

86

86.9%

6

92.9%

7

96.60%

HLA-DQB

94

94.9%

3

98.0%

2

97.20%

HLA-DRB

93

93.9%

6

100.0%

0

94.00%

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