Table 6 Recent studies on intracranial epidermoids since 2000 (n > 25).
Authors & years | No. of cases | Location (No of. cases) | Methodology | Follow-up period (Mean) | EOR (% of Patients) | Neurological functional Outcome (direct postop) | Neurological functional Outcome in follow-up (compared to direct postop) | Endoscopic assistance operations (%) | Recurrence rate |
|---|---|---|---|---|---|---|---|---|---|
Kobata et al., 200224 | 30 | CPA (30) | Retrospective Analysis | 138 mos | TR (57%) | -ND | -ND | -ND | Crude recurrence free (90%)* |
Akar et al., 200342 | 28 | CPA (17), 4th V/FM (3), sylvian fissure (4), occipital lobe (2), lateral ventricle (1), & intradiploic area (1) | Retrospective Analysis | 72 mos | Total/radical subtotal (75%), subtotal (25%) | -ND -New CN deficits: 46.4% | -ND | -ND | Crude recurrence free (93%)* |
Gopalakrishnan et al., 201428 | 50 | CPA (37), 4th Ventricle (13) | Retrospective Analysis | 111 mos | TR 62%, STR 38% | -ND | -ND | -ND | 5-yr recurrence free: -TR: 91% -STR: 7% |
Lynch et al., 201443 | 29 | CPA (13) & parasellar (6), cerebellar (5), temporal (5), & frontal (4) areas | Retrospective Analysis | 86 mos‡ | GTR (73%) & STR (27%)‡ | -ND | -ND | -ND | -ND |
Aboud et al., 201518 | 38 | Primary lesions: CPA (18), prepontine cistern (4), suprasellar (2), & MF (2) Recurrent lesions: CPA (6), suprasellar region (3), prepontine cistern (2), & parasellar region (1) | Retrospective Analysis | 56.8 mos | GTR (73% of those w/ primary lesion & 17% w/ recurrence) | -ND -New CN deficits: 45.6%, in recurrence group: 58% | -ND | -Overall: 28.2% | Crude recurrence-free (85% of those w/ primary tumor & 58% w/ recurrence) † |
Rehman et al., 201844 | 38 | CPA (18), (frontal lobe [4], temporal lobe [9], & temporal & parietal lobes w/ CS [1]), & suprasellar region (6) | Retrospective Analysis | -ND | -ND | -ND | -ND | -ND | -ND |
Vernon et al. 202020 | 139 | CPA (139) | Retrospective Analysis | 27 mos | TR 67%, NTR 3%, PR 2% | -ND -New CN deficits: 41% | -ND -Development of the new CN deficits: Better: 78% Stable: 20% Worse: 2% | -Overall: 40% | 2.5-yr recurrence free: 85% |
Hasegawa et al. 20228 | 63 | Posterior fossa (33), lobar/interhemispheric location (11), combined supratentorial & infratentorial area (11), Middle Fossa 3 & pineal region (5) | Retrospective Analysis | 88.7 mos | GTR 20%, NTR 24% STR 35% & PR 22% | -ND -New CN deficits: 31% | -ND | -ND | 5-yr recurrence free (66%) |
Present Study | 66 | CPA and prepontine (49), Supratentorial (9). 4th Ventricle (7) | Retrospective Analysis | 82.02 mos | TR 61%, NTR 27.6% STR 10.7% | -Better: 11.9% -Stable: 50% -Worse: 10.3% - New CN deficits: 27.7% | -Better: 36.4% -Stable: 51.1% -Worse: 12.4% | -Overall: 33.8% -CPA and prepontine region:36.7%, Supratentorial: 33.3%, 4th Ventricle: 14.2% | 5-yr recurrence free: TR: 95% NTR: 45% STR 30% |