Fig. 2

Evaluation of Spheroid Formation in CSC Cell Lines Treated with Diffractaic Acid and Its Analogs. Representative images of spheroid formation by CSC221 (A) and CaCo2 (B) cells treated with diffractaic acid and its analogs at 10 μM concentration for 10–14 days, and quantitative analysis of the number of spheroids formed following each treatment. Data represent the mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001.