Fig. 4 | Scientific Reports

Fig. 4

From: Development and synthesis of diffractaic acid analogs as potent inhibitors of colorectal cancer stem cell traits

Fig. 4

TU3 targets colorectal cancer stem cells by blocking cellular signaling. Western blot analysis of ALDH1, Gli1, STAT3, NF-κB, β-catenin, c-Myc and Cyclin-D1 protein levels in CSC221 (A) and CaCo2 (B) cells treated with indicated concentrations of TU3 and incubated 48 h. (C–D) Quantitative analysis of protein expression. Data represent the mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; difference compared with DMSO-treated.

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