Table 1 Demographics of the patients (N = 120) and biopsies (N = 141).
From: Relating the molecular phenotype of ulcerative colitis to the clinical course
Patient characteristics (N = 120) | UC patients (N = 112) | IBDU patients (N = 8) | |
|---|---|---|---|
Mean patient age (median, range) in years | 43 (41, 19–83) | 40 (39, 31–50) | |
Patient gender (% male) | 51 (54% male, 17 NA) | 4 (50% male, 2 NA) | |
Diagnosis | |||
Ulcerative colitis (UC) | 112 | 0 | |
Inflammatory bowel disease unclassified (IBDU) | 0 | 8 | |
Centers | |||
University of Alberta Hospital – Edmonton | 95 | 6 | |
Cedars-Sinai Medical Center – Los Angeles | 17 | 2 | |
Biopsy characteristics (N = 141) | UC biopsies (N = 128) | IBDU biopsies (N = 13) | |
|---|---|---|---|
Median time from index to last known follow-up in months (mean) | 5.1 (4.7) | 6.2 (6.2) | |
Endoscopy and biopsy indication | |||
New diagnosis | 5 | - | |
Disease activity assessment | 73 | 6 | |
Dysplasia screening | 6 | 1 | |
Fecal microbiota transplant | 1 | - | |
Cancer screening | 2 | - | |
NA | 41 | 6 | |
Disease extent | |||
Remission | 57 | 5 | |
Proctitis | 11 | 1 | |
Left-sided | 26 | 4 | |
Extensive | 4 | - | |
Pancolitis | 22 | 1 | |
NA | 8 | 2 | |
Endoscopic Mayo subscore at biopsy location | |||
0 | 24 | 1 | |
1 | 30 | 3 | |
2 | 45 | 4 | |
3 | 29 | 5 | |
Treatment regimen at the time of the biopsya | |||
5-aminosalicylic acid (topical or oral) | 62 | 4 | |
Biologic | 27 | 3 | |
Immunomodulatorb | 30 | 4 | |
Infliximab | 16 | 1 | |
Adalimumab | 4 | 2 | |
Golimumab | 2 | - | |
Vedolizumab | 4 | - | |
Other therapy | 8 | 2 | |