Table 6 Relationship between various scores at time zero and future status code (assessed at 3–6 months post-biopsy, status code >1 vs. ≤1) for all UC and IBDU biopsies (N = 141 biopsies).

From: Relating the molecular phenotype of ulcerative colitis to the clinical course

 

Variable

Mean score at time zero

Biopsies with good future status:

status code ≤ 1

Biopsies with poor future status:

status code > 1

T-test

P value

Clinical features

Total Mayo score

6.11

6.81

0.35

Physician’s global assessment

1.65

1.94

0.29

Partial Mayo score

3.26

3.75

0.51

Endoscopic Mayo subscore

1.89

2.33

0.02

Fecal calprotectin (ug/g)

758

1247

0.16

Molecular features

MayoProb1 classifier score

0.63

0.80

0.005

MayoProb2 classifier score

0.64

0.82

0.002

Molecular Calprotectin transcript set score

2.49

3.71

0.01

  1. Bold indicates significance at P < 0.05.
  2. Italic indicates the biopsy group with the highest mean score of the row when P is significant.
  3. P value was assessed using Welch’s t-test.
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