Fig. 12 | Scientific Reports

Fig. 12

From: Identification of osteoarthritis-associated chondrocyte subpopulations and key gene-regulating drugs based on multi-omics analysis

Fig. 12

The molecular expression levels of Hub genes and their associated TF were measured in clinical blood samples using RT-qPCR. (A–E) The mRNA expression levels of five hub genes (CHI3L1, CKS2, FAM26F, MMP13, and TAC1) in plasma of NC and OA groups; (F–I). The mRNA expression levels of hub genes-associated TFs (NFKB1, CREB1, CREB3, and RELA) in plasma of NC and OA groups; (J) The mRNA expression levels of HDAC6, a CAY10603 target, in plasma of NC and mRNA expression levels of HDAC6, a target of CAY10603, in plasma of OA group. (****P < 0.0001, vs. Control, N = 5, n = 3).

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