Fig. 1

Non-linear associations between De Ritis ratio and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). Restricted cubic spline regression models with fully adjusted covariates were used to explore the dose–response relationship between postoperative De Ritis levels and the risks of (A) unfavorable outcome (modified Rankin Scale score 4–6) at discharge, (B) death at discharge, (C) major adverse cardiac events (MACE), (D) abnormal hepatic function, (E) anemia, and (F) disorders of lipoprotein metabolism. Solid lines represent adjusted odds ratios (ORs) and shaded areas indicate 95% confidence intervals. Models were adjusted for age, sex, BMI, smoking, alcohol drinking, medical history, WFNS grade, modified Fisher score, aneurysm location, treatment modality, and laboratory variables including WBC, TC, TG, HDL, and LDL.