Table 1 Baseline characteristics according to quartiles of De Ritis.

From: Relationship between De Ritis and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage: Insights from the LongTEAM registry

Characteristics

Total

Quartiles of De Ritis

P value

Q1 (<0.89)

Q2 (0.89 to <1.20)

Q3 (1.20 to <1.58)

Q4 (≥1.58)

No. of the patients

1098

271

272

280

275

 

De Ritis, median (IQR)

1.20 (0.89–1.58)

0.70 (0.59–0.81)

1.05 (0.97–1.12)

1.35 (1.27–1.45)

1.92 (1.71–2.29)

<0.001

Age, median (IQR), y

55 (48–63)

51 (45–59)

55 (48–63)

58 (50–65)

56 (49–64)

<0.001

Age > 55 years old, n (%)

532 (48.5)

97 (35.8)

126 (46.3)

165 (58.9)

144 (52.4)

<0.001

BMI, median (IQR), kg/m^2

24.65 (22.83–27.06)

25.39 (23.44–27.91)

25.29 (23.18–27.92)

24.22 (22.55–26.12)

24.22 (22.33–26.04)

<0.001

Female, n (%)

646 (58.8)

136 (50.2)

165 (60.7)

178 (63.6)

167 (60.7)

0.008

Current smoking, n (%)

272 (24.8)

83 (30.6)

68 (25.0)

69 (24.6)

52 (18.9)

0.018

Current alcohol drinking, n (%)

202 (18.4)

64 (23.6)

48 (17.6)

51 (18.2)

39 (14.2)

0.041

Medical History, n (%)

 Hypertension

642 (58.5)

158 (58.3)

175 (64.3)

164 (58.6)

145 (52.7)

0.055

 Diabetes mellitus

95 (8.7)

30 (11.1)

24 (8.8)

22 (7.9)

19 (6.9)

0.348

 Hyperlipidemia

81 (7.4)

23 (8.5)

27 (9.9)

17 (6.1)

14 (5.1)

0.118

 Stroke

88 (8.0)

19 (7.0)

23 (8.5)

25 (8.9)

21 (7.6)

0.846

 Heart diseases

191 (17.4)

50 (18.5)

48 (17.6)

48 (17.1)

45 (16.4)

0.932

Admission status

 Loss of consciousness, n (%)

337 (30.7)

71 (26.2)

73 (26.8)

89 (31.8)

104 (37.8)

0.011

 WFNS 4–5, n (%)

244 (22.2)

40 (14.8)

53 (19.5)

67 (23.9)

84 (30.5)

<0.001

 mFS 3–4, n (%)

775 (69.8)

184 (67.9)

181 (66.5)

212 (75.7)

198 (72.0)

0.075

 Hydrocephalus, n (%)

431 (39.3)

108 (39.9)

99 (36.4)

117 (41.8)

107 (38.9)

0.628

 Graeb score 5–12, n (%)

90 (8.2)

13 (4.8)

24 (8.8)

24 (8.6)

29 (10.5)

0.095

 SEBES 3–4, n (%)

522 (47.5)

125 (46.1)

125 (46.0)

137 (48.9)

135 (49.1)

0.808

 Aneurysm at posterior circulation, n (%)

114 (10.4)

27 (10.0)

35 (12.9)

31 (11.1)

21 (7.6)

0.238

 Surgical clipping, n (%)

582 (53.0)

122 (45.0)

134 (49.3)

134 (47.9)

192 (69.8)

<0.001

Laboratory data, median (IQR)

 Preoperative WBC

12.43 (9.91–15.41)

12.25 (9.95–15.51)

12.53 (10.11–15.50)

12.37 (9.90–15.30)

12.54 (9.59–15.54)

0.634

 Preoperative WBC >11.28, n (%)

673 (61.3)

160 (59.0)

177 (65.1)

164 (58.6)

172 (62.5)

0.351

 Preoperative ALT, IU/L

18.40 (13.50–26.70)

31.00 (22.20–43.35)

19.60 (15.10–26.00)

15.25 (12.65–19.65)

14.00 (10.8–18.35)

<0.001

 Preoperative AST, IU/L

20.60 (16.60–27.00)

22.80 (17.65–31.00)

20.30 (16.00–25.00)

19.40 (16.00–23.95)

20.00 (17.00–27.00)

<0.001

 Total Protein, g/L

65.90 (61.40–70.40)

67.80 (63.70–71.45)

66.85 (62.50–71.50)

65.10 (61.45–69.50)

63.00 (58.05–68.45)

<0.001

 Albumin, g/L

39.10 (35.90–42.00)

40.70 (37.90–43.10)

39.70 (36.75–42.50)

38.75 (35.70–41.30)

36.90 (33.75–39.85)

<0.001

 Globulin, g/L

26.65 (24.00–29.40)

26.70 (24.40–29.65)

27.00 (24.10–29.55)

26.55 (23.90–29.30)

26.40 (23.45–28.85)

0.184

 Total bilirubine, μmol/L

14.30 (11.28–19.20)

14.80 (11.50–19.35)

14.00 (11.45–19.00)

14.05 (11.10–19.15)

14.60 (11.05–19.10)

0.802

 Total cholesterol, mmol/L

4.44 (3.85–5.15)

4.54 (3.99–5.27)

4.44 (3.90–5.16)

4.42 (3.88–5.13)

4.35 (3.77–5.08)

0.124

 Triglyceride, mmol/L

1.14 (0.85–1.57)

1.23 (0.95–1.77)

1.14 (0.87–1.69)

1.13 (0.85–1.46)

0.99 (0.76–1.41)

<0.001

 HDL, mmol/L

1.30 (1.10–1.55)

1.26 (1.07–1.50)

1.28 (1.11–1.52)

1.30 (1.09–1.57)

1.37 (1.19–1.61)

0.001

 LDL, mmol/L

2.59 (2.03–3.20)

2.75 (2.14–3.45)

2.65 (2.09–3.25)

2.57 (2.03–3.20)

2.38 (1.86–3.02)

<0.001

 ALT, IU/L

16.00 (11.90–22.80)

26.00 (18.45–34.855)

15.95 (13.00–19.65)

13.00 (10.50–17.25)

13.00 (10.00–17.60)

<0.001

 AST, IU/L

18.40 (14.20–26.33)

17.00 (13.50–22.35)

16.55 (13.20–20.25)

17.35 (14.00–23.60)

26.30 (19.10–37.55)

<0.001

 Apoprotein A1, g/L

1.24 (1.06–1.45)

1.26 (1.08–1.46)

1.27 (1.11–1.45)

1.24 (1.09–1.48)

1.19 (1.00–1.39)

0.007

 Apoprotein B, g/L

0.91 (0.77–1.08)

0.94 (0.81–1.14)

0.92 (0.78–1.11)

0.92 (0.78–1.09)

0.88 (0.73–1.03)

<0.001

  1. IQR interquartile range; BMI body mass index; WFNS World Federation of Neurological Societies Scale; mFS modified Fisher Scale; SEBES Subarachnoid Hemorrhage Early Brain Edema Score; AST aspartate aminotransferase; ALT alanine aminotransferase; De Ritis AST/ALT ratio; HDL high-density lipoprotein; LDL low-density lipoprotein.
Back to article page