Fig. 3
Average corticospinal excitability as a percentage of baseline values following repetitive AIH versus repetitive SHAM. We assessed changes in maximum motor evoked potential amplitude (MEPmax) relative to baseline (dotted red line at 100%) for both the acute intermittent hypoxia (AIH; blue) and blinded normoxia (SHAM; light grey) groups (A) MEPmax (% baseline) was significantly higher post-AIH compared to post-SHAM, indicating increased CSE only after AIH. Significance levels are denoted as *p < 0.05. (B) Individual variability in MEPmax changes on day 5 of AIH is shown as a percentage of baseline values. Each bar represents individual changes, with values above the dotted line indicating increased CSE post-AIH. The light grey bars indicate individuals who do not increase MEPmax post-AIH. An independent t-test shows MEP amplitude is significantly different than baseline MEP amplitude (p < 0.001).
