Table 3 Analyze all models for reaction particle size (Y1) and %EE (Y2).

From: Design, development, and preclinical evaluation of pirfenidone-loaded nanostructured lipid carriers for pulmonary delivery

Parameter

Source

DF

Sum squares

Mean squares

F value

P-value

SIZE (nm)

Model

9

1.147E + 05

12742.41

39.06

< 0.0001

Residual

10

3262.02

326.20

  

Lack of fit

5

3259.18

651.84

1150.30

< 0.0001

Pure error

5

2.83

0.57

  

% EE

Model

9

1842.65

204.74

38.96

< 0.0001

Residual

10

52.55

5.25

  

Lack of fit

5

51.05

10.21

34.03

0.0007

Pure error

5

1.50

0.30

  
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