Table 6 Stability statistics of dispersion-loaded NLCs PD at 4 and 25 °C.

From: Design, development, and preclinical evaluation of pirfenidone-loaded nanostructured lipid carriers for pulmonary delivery

Time

%EE

Size (nm)

PDI

Zetapotential (mV)

5 ± 2 °C

25 °C ± 2 °C

5 ± 2 °C

25 °C ± 2 °C

5 ± 2 °C

25 °C ± 2 °C

5 ± 2 °C

25 °C ± 2 °C

0

81.4 ± 7.1

81.4 ± 7.1

159.8 ± 3.46

159.8 ± 3.46

0.13 ± 0.03

0.13 ± 0.03

-32.5 ± 0.64

-32.5 ± 0.64

1

80.3 ± 1.05

80.9 ± 2.41

168.3 ± 5.64

165.3 ± 6.23

0.15 ± 0.02

0.14 ± 0.06

-30.2 ± 0.12

-29.6 ± 0.05

3

77.9 ± 0.09

78.6 ± 0.94

172.1 ± 2.91

16,938 ± 8.15

0.17 ± 0.04

015 ± 0.04

-28.4 ± 0.31

-27.1 ± 0.09

6

72.5 ± 1.35

76.1 ± 1.65

190.3 ± 3.46

178.4 ± 4.29

0.19 ± 0.01

0.16 ± 0.02

-26.1 ± 0.26

-25.8 ± 0.01

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