Fig. 7

Identification and Validation of Key Genes in the Immune Risk Model. (A) Box plots illustrating the differential expression of key genes between high-risk and low-risk groups. (B) Protein-protein interaction network of the key genes, showing strong co-expression relationships. (C) Mutation waterfall plot of key genes in melanoma, predominantly featuring missense mutations, with the highest mutation frequencies observed in CD2 (34%), ITK (34%), and GZMA (21%). (D) Immunofluorescence staining of CD247 and CD8 in high-risk and low-risk groups.