Fig. 5 | Scientific Reports

Fig. 5

From: The c.119-123dup5bp mutation in human γC-crystallin destabilizes the protein and activates the unfolded protein response to cause highly variable cataracts

Fig. 5

Activation of genes expressed in the UPR. (A). Expression changes of genes in the UPRer pathway with the location within the cell indicated. (B). Expression changes of genes in the UPRmt pathway. Expression levels are indicated by the shading of genes: increased expression is indicated by red shading, decreased expression is indicated by green shading, and genes whose expression changes less than 1.2-fold are shaded grey. The depth of shading is proportional to the fold change in expression. Processes predicted to be increased are shaded yellow.

Back to article page