Fig. 7 | Scientific Reports

Fig. 7

From: The c.119-123dup5bp mutation in human γC-crystallin destabilizes the protein and activates the unfolded protein response to cause highly variable cataracts

Fig. 7

Activation of genes in signaling pathways mediating the UPR influences on autophagy and apoptosis: Atf6 signaling pathways. Expression levels are indicated by the shading of genes: increased expression is indicated by red shading, decreased expression is indicated by green shading, and genes whose expression changes less than 1.2-fold are shaded grey. The depth of shading is proportional to the fold change in expression. Processes predicted to be increased are shaded yellow.

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