Table 2 Baseline characteristics of BCS and TM in the modeling group of T1 LABC patients.

From: Establishment and validation survival prediction models for T1 locally advanced breast cancer after breast conservation surgery versus mastectomy

Characteristics

BCS

TM

t/χ²

P value

Age (M ± SD)

59.85 ± 12.20

59.89 ± 13.31

− 0.090

0.929

Race, n (%)

 White

1045 (77.5)

1047 (76.5)

10.373

0.016

 Black

196 (14.5)

186 (13.6)

  

 Other

96 ( 7.1)

132 ( 9.6)

  

 Unknown

11 ( 0.8)

3 ( 0.2)

  

Pathological type, n%

 Metaplastic carcinoma

2 ( 0.1)

2 ( 0.1)

10.170

0.118

 Infiltrating duct carcinoma

1065 (79.0)

1015 (74.2)

  

 Lobular carcinoma

129 ( 9.6)

148 (10.8)

  

 Ductal carcinoma, micropapillary

10 ( 0.7)

11 ( 0.8)

  

 Medullary carcinoma

3 ( 0.2)

3 ( 0.2)

  

 Mucinous adenocarcinoma

3 ( 0.2)

3 ( 0.2)

  

 Others

136 (10.1)

186 (13.6)

  

Grade, n%

 III

538 (39.9)

539 (39.4)

3.345

0.502

 I

179 (13.3)

164 (12.0)

  

 II

588 (43.6)

606 (44.3)

  

 IV

5 ( 0.4)

6 ( 0.4)

  

 Unknown

38 ( 2.8)

53 ( 3.9)

  

T, n%

 T1a

34 ( 2.5)

61 ( 4.5)

9.654

0.047

 T1mic

7 ( 0.5)

11 ( 0.8)

  

 T1b

166 (12.3)

181 (13.2)

  

 T1c

1134 (84.1)

1110 (81.1)

  

 T1NOS

7 ( 0.5)

5 ( 0.4)

  

N, n%

 N2

1001 (74.3)

935 (68.3)

11.298

0.001

 N3

347 (25.7)

433 (31.7)

  

ER, n%

 Unknown

26 ( 1.9)

17 ( 1.2)

3.892

0.143

 Positive

1085 (80.5)

1081 (79.0)

  

 Negative

237 (17.6)

270 (19.7)

  

PR, n%

 Unknown

32 ( 2.4)

21 ( 1.5)

7.1785

0.028

 Positive

921 (68.3)

890 (65.1)

  

 Negative

395 (29.3)

457 (33.4)

  

HER2, n%

 Unknown

64 ( 4.7)

65 ( 4.8)

7.811

0.020

 Positive

222 (16.5)

282 (20.6)

  

 Negative

1062 (78.8)

1021 (74.6)

  

Molecular subtype, n%

 HER2 enriched

72 ( 5.3)

94 ( 6.9)

10.227

0.069

 Luminal A

917 (68.0)

863 (63.1)

  

 Luminal B

44 ( 3.3)

63 ( 4.6)

  

 Triple positive

106 ( 7.9)

125 ( 9.1)

  

 Triple negative

142 (10.5)

158 (11.5)

  

 Unknown

67 ( 5.0)

65 ( 4.8)

  

Primary Site, n%

 Upper-inner quadrant

127 ( 9.4)

103 ( 7.5)

128.590

< 0.001

 Nipple/ Central portion

40 ( 3.0)

91 ( 6.7)

  

 Lower-inner quadrant

74 ( 5.5)

65 ( 4.8)

  

 Upper-outer quadrant

549 (40.7)

413 (30.2)

  

 Lower-outer quadrant

159 (11.8)

125 ( 9.1)

  

 Axillary Tail

17 ( 1.3)

12 ( 0.9)

  

 Overlapping lesion

270 (20.0)

265 (19.4)

  

 Breast

112 ( 8.3)

294 (21.5)

  

Chemotherapy, n%

 No

278 (20.6)

270 (19.7)

0.278

0.598

 Yes

1070 (79.4)

1098 (80.3)

  

RT, n%

 No

17 ( 1.3)

27 ( 2.0)

19.142

< 0.001

 Yes

900 (66.8)

804 (58.8)

  

Unknown

431 (32.0)

537 (39.3)

  
  1. LABC locally advanced breast cancer, BCS breast-conserving surgery, TM total mastectomy, M ± SD mean ± standard deviation, NOS not otherwise specified, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, RT radiotherapy.