Fig. 5
From: Dapagliflozin inhibits ferroptosis and ameliorates renal fibrosis in diabetic C57BL/6J mice
The effects of DAPA on oxidative stress in mice kidney tissue. (a) The levels of SOD. (b) The levels of GSH. (c) The levels of MDA. (d) The levels of LDH. (e) The levels of CAT. (f) Detection of Nrf2/HO-1 pathway marker protein by WB. (g) The WB analysis of Nrf2/GAPDH. (h) The WB analysis of HO-1/GAPDH. (i) Detection of Nrf2/HO-1 pathway by IHC. Magnification: 400×. The scale bar represents a length of 50 μm. (j) The IHC analysis of Nrf2. (k) The IHC analysis of HO-1. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001).
