Fig. 4
From: Glaucocalyxin A alleviates ulcerative colitis by inhibiting PI3K/AKT/mTOR signaling

GLA suppresses the LPS-induced increase in the expression of inflammatory components in a macrophage model of inflammation in RAW264.7 cells. (A) Chemical Structure of Glaucocalyxin A. (B) Assessment of the Cytotoxicity of Different GLA Concentrations on Raw264.7 Cells. (C) With increasing GLA concentration, IL-10 expression increases. (D) With increasing GLA concentration, IL-6 expression decreases. (E) With increasing GLA concentration, IL-1β, expression decreases. (F) With increasing GLA concentration, TNF-α expression decreases. (*p < 0.05; **p < 0.01; and ***p < 0.001 relative to the control).