Fig. 6 | Scientific Reports

Fig. 6

From: Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis

Fig. 6

WT stands for the wild-type gene of hsa_circ_0074763, while Mut represents the mutant form of the same gene.Hsa_circ_0074763 acts as a sponge of miR-3667-3p (A-B) The mRNA expressions of ACSL4 were detected by qRT PCR assay after miR-3667-3p mimics/miR-3667-3p inhibitor.(C) Dual-luciferase reporter gene assay verified the binding relationship between hsa_circ_0074763 and miR-3667-3p. (D) The mRNA expressions of hsa_circ_004763 were detected by qRT PCR assay after miR-3667-3p mimics/miR-3667-3p inhibitor. (E) The mRNA expressions of miR-3667-3p were detected by qRT PCR assay after LV-hsa_circ_0074763/si-hsa_circ_0074763. *P < 0.05; **P < 0.01. n = 3.

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