Table 1 Patient characteristics by receipt of ALND in SJTUBCDB.

From: The impact of axillary lymph node dissection on the prognosis of breast cancer patients undergoing up-front mastectomy with Sentinel lymph node micrometastases

Characteristics

All N(%)

Non-ALND Group

ALND Group

P value

Year of diagnose

2013–2016

35 (29.7)

16 (34.8)

19 (26.4)

0.443

2017–2020

83 (70.3)

30 (65.2)

53 (73.6)

 

Age (years)

    

< 49

59 (50.0)

28 (60.9)

31 (43.1)

0.168

50–64

47 (39.8)

16 (34.8)

31 (43.1)

 

> 65

12(10.2)

2(4.3)

10(13.9)

 

Menopausal status

Pre

68 (57.6)

32 (69.6)

36 (50.0)

0.057

Post

50 (42.4)

14 (30.4)

36 (50.0)

 

Histology

IDC

99 (83.9)

33 (71.7)

66 (91.7)

0.013

ILC

1 (0.8)

1 (2.2)

0 (0.0)

 

Others

18 (15.3)

12 (26.1)

6 (8.3)

 

Grade

I

12 (10.2)

5 (10.9)

7 (9.7)

0.764

II

68 (57.6)

28 (60.9)

40 (55.6)

 

III

38 (32.2)

13 (28.3)

25 (34.7)

 

T stage

T1

65 (55.1)

30 (65.2)

35 (48.6)

0.114

T2

53 (44.9)

16 (34.8)

37 (51.4)

 

Ki67

≤ 20

47 (39.8)

17 (37.0)

30 (41.7)

0.751

>20

71 (60.2)

29 (63.0)

42 (58.3)

 

Subtype

HR+/HER2-

87 (73.8)

29 (63.1)

58 (80.6)

0.123

HR+/HER2+

13 (11.0)

6 (13.0)

7 (9.7)

 

HR-/HER2+

13 (11.0)

7 (15.2)

6 (8.3)

 

HR-/HER2-

5 (4.2)

4 (8.7)

1 (1.4)

 

LVI

No

99 (83.9)

40 (87.0)

59 (81.9)

0.641

Yes

19 (16.1)

6 (13.0)

13 (18.1)

 

Number of sentinel-nodes removed

1

7 (5.9)

1 (2.2)

6 (8.3)

0.677

2

15 (12.7)

7 (15.2)

8 (11.1)

 

3

37 (31.4)

13 (28.3)

24 (33.3)

 

4

23 (19.5)

9 (19.6)

14 (19.4)

 

5

14 (11.9)

7 (15.2)

7 (9.7)

 

≥ 6

22 (18.6)

9 (19.6)

13 (18.1)

 

Number of metastatic sentinel-nodes

1

108 (91.5)

43 (93.5)

65 (90.3)

0.787

2

10 (8.5)

3 (6.5)

7 (9.7)

 

Chemotherapy

    

No

18 (15.3)

7 (15.2)

11 (15.3)

1

Yes

100 (84.7)

39 (84.8)

61 (84.7)

 

Radiotherapy

No

104 (88.1)

46 (100.0)

58 (80.6)

0.004

Yes

14 (11.9)

0 (0.0)

14 (19.4)

 

Endocrine therapy

No

28 (23.7)

15 (32.6)

13 (18.1)

0.112

Yes

90 (76.3)

31 (67.4)

59 (81.9)

 

Targeted therapy

No

96 (81.4)

38 (82.6)

58 (80.6)

0.971

Yes

22 (18.6)

8 (17.4)

14 (19.4)

 
  1. ALND axillary lymph node dissection, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, HR hormone receptor, HER2 human epidermal growth factor 2, LVI lymphovascular invasion.