Fig. 2 | Scientific Reports

Fig. 2

From: Endocardial-to-mesenchymal transition underlies cardiac outflow tract septation and bicuspid aortic valve formation in the Syrian hamster model

Fig. 2

Transverse sections of the OFT of ED12 (a–i) and ED11 (j–l) hamster embryos with TAV from T and control strains (a–c) and BAV from T strain (d–l), stained with the TUNEL assay (green; a–c, g–k) or with caspase antibodies (red; d–l). Nuclei were stained with DAPI (blue). The red rectangles show magnifications of the thoracic wall (b,e), the CS (c,f) and the area of fusion of the CRs (i,l). The fusion area shown in (j–l) corresponds to the H-E stained section in Fig. 1e,m, and that shown in (g,i) corresponds to Fig. 1i. Arrows in i and l delimit the fusion area. Arrowheads point to apoptotic cells. Scale bar for insets: 100 μm. Scale bar for magnifications: 50 μm.

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