Table 3 Mutations validation.
Serial No | nsSNPs | SIFT | Polyphene-2 | Provean | SNAP2 | I-Mutant | MUpro |
|---|---|---|---|---|---|---|---|
1 | V29Y | Deleterious (< 0.05) | Unknown | Disease | Effect protein structure (score = 61) | Decrease | Decrease (− 1.33) |
2 | S30E | Deleterious (< 0.05) | Benign (0.001) | Disease | Effect protein structure (score = 54) | Decrease | Decrease (− 0.74) |
3 | F31Y | Deleterious (< 0.05) | Benign (0.002) | Disease | Effect protein structure (score = 25) | Decrease | Decrease (− 1.24) |
4 | Q32T | Deleterious (< 0.05) | Benign (0.009) | Disease | Effect protein structure (score = 15) | Decrease | Decrease (− 0.88) |
5 | K34D | Deleterious (< 0.05) | Benign (0.000) | Disease | Effect protein structure (score = 50) | Decrease | Decrease (− 0.58) |
6 | F36I | Deleterious (< 0.05) | Possibly damaging (0.824) | Disease | Effect protein structure (score = 52) | Decrease | Decrease (− 0.9) |
