Fig. 5
From: Knockdown of LncRNA MEG3 promotes damage of vascular endothelial cells induced by vibration
Vibration treatment of MEG3 knockdown HUVECs induces cells injury. (A and B) Intracellular structural changes of cells in 20 Hz, two-day group (A) and 125 Hz, two-day group (B) were respectively observed at different magnifications of 1 μm-10 kx, 0.5 μm-25 kx, 1 μm-10 kx, 0.5 μm-30 kx, and 2 μm-5 kx. Nucleus pyknosis, abnormal chromatin or chromatin margination, swollen endoplasmic reticulum and mitochondria and vacuolization are indicated with red arrows. (C to F) Effect of vibration on cell viability in each group. N = 5 experimental replicates per group. *P < 0.05, **P < 0.01, compared with the negative control group.
