Table 1 The list of the 61 high-confidence NGB interactors identified by AP-MS.
From: Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells
Gene names | Protein IDs | Protein names | –Log(P-value) | Difference* | CRAPome score# |
|---|---|---|---|---|---|
NGB | Q9NPG2 | Neuroglobin | 4.489 | 13.9 | 0 / 716 |
KCTD2 | Q14681 | BTB/POZ domain-containing protein KCTD2 | 2.273 | 5.1 | 13 / 716 |
CREBBP | Q92793 | CREB-binding protein | 2.544 | 4.8 | 18 / 716 |
ADCY8 | P40145 | Adenylate cyclase type 8 | 3.313 | 4.8 | 0 / 716 |
QRICH1 | Q2TAL8 | Glutamine-rich protein 1 | 2.130 | 4.7 | 12 / 716 |
RPTOR | Q8N122 | Regulatory-associated protein of mTOR | 1.125 | 4.6 | 14 / 716 |
METTL13 | Q8N6R0 | Methyltransferase-like protein 13 | 2.389 | 4.4 | 2 / 716 |
TMCO1 | Q9UM00 | Transmembrane and coiled-coil domain-containing protein 1 | 2.420 | 4.1 | 30 / 716 |
IL1RL1 | Q01638 | Interleukin-1 receptor-like 1 | 2.482 | 4.0 | 0 / 716 |
COQ5 | Q5HYK3 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | 2.808 | 3.9 | 2 / 716 |
KRCC1 | Q9NPI7 | Lysine-rich coiled-coil protein 1 | 1.916 | 3.8 | 0 / 716 |
SLC30A9 | Q6PML9 | Zinc transporter 9 | 1.400 | 3.8 | 1 / 716 |
SURF2 | Q15527 | Surfeit locus protein 2 | 3.153 | 3.8 | 0 / 716 |
MIEN1 | Q9BRT3 | Migration and invasion enhancer 1 | 2.142 | 3.8 | 3 / 716 |
TSSC4 | Q9Y5U2 | Protein TSSC4 | 2.829 | 3.7 | 5 / 716 |
WDR37 | Q9Y2I8 | WD repeat-containing protein 37 | 2.392 | 3.6 | 0 / 716 |
UQCRQ | O14949 | Cytochrome b-c1 complex subunit 8 | 1.557 | 3.6 | 5 / 716 |
SCAMP4 | Q969E2 | Secretory carrier-associated membrane protein 4 | 2.716 | 3.6 | 2 / 716 |
HTT | P42858 | Huntingtin | 2.051 | 3.5 | 19 / 716 |
TMEM126A | Q9H061 | Transmembrane protein 126 A | 4.228 | 3.5 | 3 / 716 |
C17orf62 | Q9BQA9 | Uncharacterized protein C17orf62 | 1.752 | 3.5 | 0 / 716 |
APOOL | Q6UXV4 | MICOS complex subunit MIC27 | 2.052 | 3.5 | 2 / 716 |
GPNMB | Q14956 | Transmembrane glycoprotein NMB | 1.922 | 3.4 | 3 / 716 |
KIAA1033 | Q2M389 | WASH complex subunit 7 | 2.190 | 3.4 | 17 / 716 |
AGPAT5 | Q9NUQ2 | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon | 2.490 | 3.4 | 4 / 716 |
SOGA3 | Q5TF21 | Protein SOGA3 | 3.097 | 3.4 | 0 / 716 |
PIGK | Q92643 | GPI-anchor transamidase | 1.750 | 3.4 | 8 / 716 |
UBR7 | Q8N806 | Putative E3 ubiquitin-protein ligase UBR7 | 3.022 | 3.4 | 6 / 716 |
TBC1D5 | Q92609 | TBC1 domain family member 5 | 2.987 | 3.3 | 28 / 716 |
KCTD17 | Q8N5Z5 | BTB/POZ domain-containing protein KCTD17 | 1.960 | 3.3 | 10 / 716 |
ILK | Q13418 | Integrin-linked protein kinase | 3.691 | 3.3 | 10 / 716 |
PIGT | Q969N2 | GPI transamidase component PIG-T | 2.859 | 3.3 | 7 / 716 |
PHF23 | Q9BUL5 | PHD finger protein 23 | 2.295 | 3.3 | 1 / 716 |
SLC30A7 | Q8NEW0 | Zinc transporter 7 | 2.274 | 3.3 | 2 / 716 |
VTI1B | Q9UEU0 | Vesicle transport through interaction with t-SNAREs homolog 1B | 2.701 | 3.2 | 3 / 716 |
UBAC2 | Q8NBM4 | Ubiquitin-associated domain-containing protein 2 | 2.891 | 3.2 | 11 / 716 |
EPB41L5 | Q9HCM4 | Band 4.1-like protein 5 | 3.292 | 3.2 | 9 / 716 |
C2orf43 | Q9H6V9 | UPF0554 protein C2orf43 | 3.420 | 3.2 | 0 / 716 |
YME1L1 | Q96TA2 | ATP-dependent zinc metalloprotease YME1L1 | 1.925 | 3.2 | 28 / 716 |
SLC25A17 | O43808 | Peroxisomal membrane protein PMP34 | 1.948 | 3.2 | 5 / 716 |
RHBDD2 | Q6NTF9 | Rhomboid domain-containing protein 2 | 3.835 | 3.1 | 19 / 716 |
ARIH1 | Q9Y4 × 5 | E3 ubiquitin-protein ligase ARIH1 | 2.205 | 3.1 | 5 / 716 |
IWS1 | Q96ST2 | Protein IWS1 homolog | 2.187 | 3.1 | 21 / 716 |
WBSCR22 | O43709 | Probable 18 S rRNA (guanine-N(7))-methyltransferase | 2.704 | 3.1 | 17 / 716 |
SPTLC2 | O15270 | Serine palmitoyltransferase 2 | 3.549 | 3.1 | 3 / 716 |
NMD3 | Q96D46 | 60 S ribosomal export protein NMD3 | 2.089 | 3.1 | 10 / 716 |
NEMF | O60524 | Nuclear export mediator factor NEMF | 3.202 | 3.1 | 11 / 716 |
OXA1L | Q15070 | Mitochondrial inner membrane protein OXA1L | 2.051 | 3.1 | 10 / 716 |
RALGAPA1 | Q6GYQ0 | Ral GTPase-activating protein subunit alpha-1 | 3.181 | 3.0 | 11 / 716 |
AKR1C1 | Q04828 | Aldo-keto reductase family 1 member C1 | 2.948 | 3.0 | 10 / 716 |
SCYL1 | Q96KG9 | N-terminal kinase-like protein | 3.321 | 3.0 | 12 / 716 |
MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase £kinase 7 | 2.693 | 2.9 | 3 / 716 |
C2CD5 | Q86YS7 | C2 domain-containing protein 5 | 2.937 | 2.9 | 5 / 716 |
CBL | P22681 | E3 ubiquitin-protein ligase CBL | 2.762 | 2.9 | 18 / 716 |
DDHD2 | O94830 | Phospholipase DDHD2 | 2.845 | 2.9 | 2 / 716 |
YIF1A | O95070 | Protein YIF1A | 2.498 | 2.9 | 2 / 716 |
C18orf25 | Q96B23 | Uncharacterized protein C18orf25 | 2.378 | 2.9 | 15 / 716 |
PGM2 | Q96G03 | Phosphoglucomutase-2 | 2.556 | 2.8 | 25 / 716 |
EHD1 | Q9H4M9 | EH domain-containing protein 1 | 2.402 | 2.8 | 5 / 716 |
SS18L1 | O75177 | Calcium-responsive transactivator | 2.958 | 2.7 | 17 / 716 |
DDA1 | Q9BW61 | DET1- and DDB1-associated protein 1 | 4.031 | 2.5 | 4 / 716 |
