Table 1 Clinical characteristics between healthy controls, CH and hepatitis B-related ACLF patients.

From: High glycosylated serum protein to high density lipoprotein cholesterol ratios are predictive of worse acute on chronic liver failure prognoses

Characteristics

Healthy Control

CH

ACLF

P value

Gender, male/female (n)

7/13

38/16

754/107

< 0.001

Hospital stay

N/A

6.00 (4.00, 11.00)

24 (14–42)

< 0.001

Age (years)

41 (33–65)

49.00 (41.00, 58.25)

43 (35–51)

0.007

ALT (U/L)

12.9 (11.2–16.5)

41.50 (18.92, 136.30)

710.0 (237.5-1329.5)

< 0.001

AST (U/L)

19.4 (17.7–21.9)

46.05 (24.62, 90.53)

443.0 (173.9–957.0)

< 0.001

TBil (µmol/L)

14.0 (11.3–16.2)

19.10 (12.77, 35.05)

273.8 (192.1-364.7)

< 0.001

DBIL (µmol/L)

2.5 (2.3–2.9)

4.70 (3.20, 14.18)

173.0 (122.6–237.0)

< 0.001

ALB (g/L)

43.6 (42.3–44.6)

36.70 (33.40, 40.90)

32.8 (29.6–35.7)

< 0.001

GLB (g/L)

29.6 (28.6–32.1)

28.50 (25.90, 31.30)

25.8 (22.1–30.6)

< 0.001

Cr (µmol/L)

61.7 (50.9–78.9)

71.25 (59.67, 79.90)

64.1 (56.9–74.3)

0.049

GGT

17.5 (10.5–22.8)

57.00 (28.00, 179.00)

97.0 (63.5-145.7)

< 0.001

FBG (mmol/L)

5.26 (4.85–5.59)

4.86 (4.49, 6.15)

4.07 (3.31–5.69)

< 0.001

GSP

1.92 (1.81–2.03)

2.69 (2.00, 2.69)

3.72 (3.18–4.21)

< 0.001

TC (mmol/L)

4.31 (3.68–5.04)

3.76 (3.18, 4.25)

2.51 (1.98–3.02.)

< 0.001

TG (mmol/L)

1.58 (1.15–1.89)

1.23 (0.82, 1.70)

1.07 (0.73–1.62)

0.01

HDL-c (mmol/L)

1.31 (1.08–1.79)

1.27 (1.01, 1.55)

1.17 (0.45–1.30)

< 0.001

LDL-c (mmol/L)

1.34 (0.96–1.81)

2.10 (1.47, 2.46)

1.13 (0.67–1.59)

< 0.001

Na+ (mmol/L)

141.6 (138.9–143.0)

139.90 (137.50, 142.07)

137.5 (135.0-139.7)

< 0.001

PT (seconds)

11.2 (10.6–11.9)

13.10 (12.40, 14.55)

23.7 (19.9–29.2)

< 0.001

PTA

92.3 (80.0-106.7)

81.35 (72.65, 98.25)

32.5 (25.0-39.8)

< 0.001

INR

0.91 (0.88–1.01)

1.11 (1.01, 1.19)

2.11 (1.76–2.62)

< 0.001

WBC count (×109/L)

6.28 (4.72–7.10)

4.92 (3.53, 6.56)

6.24 (4.79–7.96)

< 0.001

HGB (g/L)

133 (128–141)

122.50 (107.25, 138.75)

132 (118–146)

0.069

Platelet count (×109/L)

251 (196–269)

143.50 (76.25, 196.50)

116 (81–153)

< 0.001

NEUT (×109/L)

3.58 (2.37–4.51)

2.88 (1.65, 3.92)

4.07 (2.90–5.63)

< 0.001

Lymphocyte count (×109/L)

1.99 (1.52–2.31)

1.50 (0.84, 2.04)

1.20 (0.91–1.62)

< 0.001

AFP

2.69 (2.30–3.83)

2.80 (1.70, 5.79)

62.50 (18.53-148.93)

< 0.001

MELD score

1.78 (-0.50-3.799)

5.76 (3.51, 8.93)

22.13 (19.27–25.63)

< 0.001

i-MELD score

15.24 (13.02–24.13)

24.25 (19.79, 34.08)

43.80 (36.66-125.76)

< 0.001

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