Table 1 Baseline characteristics of the glaucoma groups.
Characteristics | Stable group (nā=ā41 patients) (nā=ā47 eyes) | Progressive group (nā=ā21 patients) (nā=ā24 eyes) | p-valuea |
|---|---|---|---|
Age (y) | 44.85ā±ā10.22 | 49.52ā±ā12.27 | 0.091 |
Gender (male: female) | 32:9 | 11:10 | 0.038 |
Eye (OD: OS) | 23:24 | 17:7 | 0.078 |
Spherical equivalence (D) | ā8.47ā±ā2.62 | ā8.55ā±ā2.14 | 0.491 |
Visual field measurement | 0.081 | ||
Ā MD:>ā6 | 37 (78.7%) | 13 (54.2%) | Ā |
Ā MD:ā12 to ā6 | 6 (12.8%) | 8 (33.3%) | Ā |
Ā MD:<ā12 | 4 (8.5%) | 3 (12.5%) | Ā |
Baseline Visual field index (%) | 90.49ā±ā13.33 | 79.63ā±ā21.26 | 0.001 |
Ā Final Visual field index (%) | 90.87ā±ā12.83 | 75.04ā±ā18.71 | <ā0.001 |
Baseline Mean deviation (dB) | ā3.89ā±ā4.45 | ā6.77ā±ā4.63 | 0.004 |
Ā Final Mean deviation (dB) | ā3.47ā±ā4.04 | ā9.47ā±ā5.47 | <ā0.001 |
Peripapillary RNFL measurement | Ā | ||
Ā Baseline mean RNFL thickness | 78.11ā±ā10.23 | 71.50ā±ā7.13 | 0.003 |
Ā Final mean RNFL thickness | 75.13ā±ā9.33 | 67.17ā±ā7.28 | <ā0.001 |
Macular GCIPL measurement | Ā | ||
Ā Baseline mean GCIPL thickness | 68.23ā±ā8.06 | 61.92ā±ā9.25 | 0.007 |
Ā Final mean GCIPL thickness | 66.32ā±ā8.74 | 60.21ā±ā8.39 | 0.008 |
Optic disc area (\(\:{\text{mm}}^{2}\)) | 1.91ā±ā0.46 | 1.80ā±ā0.58 | 0.098 |
Rim area (mm) | 0.92ā±ā0.20 | 0.69ā±ā0.20 | <ā0.001 |
Average C/D ratio (%) | 0.69ā±ā0.09 | 0.76ā±ā0.10 | 0.017 |
OCT examination | 4.53ā±ā0.86 | 5.50ā±ā1.18 | 0.001 |
Follow-up period (year) | 2.89ā±ā0.62 | 2.86ā±ā0.88 | 0.794 |
Mean macular perfusion density (/mm)(outer) | 15.77ā±ā2.41 | 14.37ā±ā2.81 | 0.060 |
Mean macular perfusion density (/mm)(full) | 15.71ā±ā2.40 | 14.45ā±ā2.80 | 0.080 |
Optic disc perfusion density(outer) | 16.31ā±ā2.60 | 15.18ā±ā4.09 | 0.559 |
Optic disc perfusion density(full) | 15.54ā±ā2.34 | 14.17ā±ā3.74 | 0.316 |
Intraocular pressure (IOP, mm Hg) | Ā | ||
Ā Baseline IOP | 15.91ā±ā3.07 | 16.60ā±ā4.80 | 0.635 |
Ā Mean follow-up IOP | 14.56ā±ā1.69 | 15.58ā±ā2.43 | 0.008 |
Ā Peak IOP | 18.36ā±ā3.11 | 22.00ā±ā4.92 | <ā0.001 |
Central corneal thickness | 548.21ā±ā32.85 | 541.42ā±ā32.38 | 0.527 |