Fig. 3

While novel object recognition is similar to wild type mice, Slc6a8^-/y mice show abnormalities in conditioned fear testing. (A) Novel object recognition testing demonstrates no statistically significant difference between Slc6a8^-/y and WT mice. Conditioned/contextual fear testing was performed with (B) acquisition phase, (C) context testing, (D) context testing over time, (E) extinguish testing, and (F) testing for reinstatement of conditioned fear response. All data is presented as mean + SD. WT = wild type. P values of ≤ 0.05 are shown with one (*) asterisk, ≤ 0.01 are shown with two (**), and between 0.0001 and 0.001 are shown with three (***).