Fig. 1 | Scientific Reports

Fig. 1

From: Genome-wide association and multi-omics analyses provide insights into the disease mechanisms of central serous chorioretinopathy

Fig. 1

Manhattan plots of the discovery stage of the genome-wide meta-analysis for central serous chorioretinopathy (CSC). The plots represent the − log10 transformed P-values for all single nucleotide polymorphisms. The red and blue horizontal lines represent the genome-wide significant threshold (P = 5.0 × 10–8) and the suggestive threshold (P = 5.0 × 10–7), respectively. Seven loci (arrows), including previously reported susceptibility loci for CSC (CFH, TNFRSF10A-TNFRSF10A-DT, and near GATA5) associate with CSC genome-wide significantly, and six loci (arrowheads) associate with CSC suggestively.

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