Fig. 1

Analysis of cell death morphology after heat shock. (a) Density plot of Annexin-DAPI method after the heat shock up to 24 h. A2780 and SKOV3 cells were heated for 1 h at 46°C, and cell death patterns were analyzed at 0 (non-heated), 1, 3, 8, 16, 24 h. (b and c) Time profiles of apoptotic and necrotic cells treated with heat shock. The blue and red lines represent the results of A2780 and SKOV3 cells, respectively. Mean ± S.D.; n = 3 ~ 4. Student’s t-test. ***P < 0.001.